Factors associated with infertility in women less than 25 years

Authors

  • Nsahlai CJ Faculty of Medicine and Biomedical Sciences, The University of Yaoundé I
  • Dohbit Sama J
  • Metogo Ntsama JA
  • Mpono Emenguele P
  • Nyada SR
  • Ngono Akam Marga V
  • Mboua Batoum VS
  • Ebong Ebontane C
  • Mve Koh V

DOI:

https://doi.org/10.64294/jsd.v3i4.184

Abstract

Background: Infertility among women at peak reproductive potential, is a growing concern in resource-limited settings. Preventable causes like untreated sexually transmitted infections (STIs), unsafe abortions, and postpartum infections are common. This study examined factors associated with infertility in young women in Yaoundé.

Methodology: We conducted a retrospective case–control study of 150 women aged 21–25 years from two referral hospitals between 1st January and 31st December 2021. Cases: women consulting for infertility (n = 75) and controls: postpartum women matched by age (n = 75). Data were analyzed using Chi-square/Fisher’s exact tests and multivariate logistic regression. Adjusted odds ratios (AOR) with 95% confidence intervals (CI) were calculated; significance was p < 0.05.

Results: Primary infertility accounted for 81.3% of cases. Leading causes included genital tract infections (47.5%), tubal obstruction/adhesions (22.0%), and polycystic ovary syndrome (11.9%). Independent predictors of infertility were being in union (AOR 8.08, 95% CI 2.34–27.94), unemployment (AOR 67.21, 95% CI 3.76–1201.49), precocious menarche (AOR 9.30, 95% CI 1.03–83.86), history of STI (AOR 8.52, 95% CI 1.56–46.58), obesity (AOR 64.85, 95% CI 4.41–953.59), and alcohol use (AOR 45.41, 95% CI 8.79–234.76). Secondary education was protective (AOR 0.14, 95% CI 0.03–1.06). Financial barriers prevented diagnostic evaluation in 21.3% of cases.

Conclusion: Infertility is strongly linked to preventable and modifiable factors. Interventions focused on STI prevention, lifestyle modification, reproductive health education, and reducing financial barriers are essential to mitigate this burden.

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Published

18-12-2025

How to Cite

Nsahlai CJ, et al. “Factors Associated With Infertility in Women Less Than 25 Years”. Journal of Science and Diseases, vol. 3, no. 4, Dec. 2025, pp. 18-24, doi:10.64294/jsd.v3i4.184.

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Original Article

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