Spindle Cell Variant of uterine embryonal Rhabdomyosarcoma: therapeutic and diagnostic challenges in low resource setting

Abstract

The spindle cell variant of embryonal rhabdomyosarcoma is a rare variant and better differentiated from all other types of embryonal rhabdomyosarcoma variants. It usually occurs in childhood and is generally associated with a good prognosis when diagnosed early with the complete panel necessary, but it becomes a whole different story at the advanced stage, despite its low malignant potential. A 3-year-old girl with stage 4 embryonal spindle cell rhabdomyosarcoma underwent 15 cycles of chemotherapy with actynomycin-D, cyclophosphamide and vincristine, the course was marked by disease progression and death. Spindle cell embryonal rhabdomyosarcoma is a rare variety, and its prognosis depends on the stage of presentation, and rapidity of diagnosis.